Ramos quits to pave way for Spurs Juande Ramos has resigned as Sevilla coach and seems set to become Tottenham manager following Martin Jol's sacking. Spanish football journalist Graham Hunter told BBC Radio 5 Live: "Spurs are on the verge of getting their man."
According to reports in Spain, Ramos has agreed a four-year deal and is expected to join Spurs on Monday.
Without mentioning Tottenham by name, the 53-year-old Ramos told his personal website: "For my family and career it is impossible not to leave for London."
The Evening Standard newspaper reported Ramos would be paid £25m over the length of his contract.
"This has been the hardest decision of my life," added Ramos. "My time at Sevilla has been the most important period of my life personally and professionally. I will be eternally grateful."
Ramos, who has managed 10 clubs in 14 years, led Sevilla to the Uefa Cup title in each of the last two seasons and into the Champions League for the first time.
Sevilla's physical trainer Marcos Alvarez has also tendered his resignation.
Ramos' contract with Sevilla had been due to expire at the end of this season.
"The now ex-Sevilla coach declined the possibility of giving a press conference at the club's training facilities," said a Sevilla statement.
"He has chosen his website www.juanderamos.com as a means of saying goodbye to Sevilla."
It is thought that Ramos wants to install Leeds assistant boss Gus Poyet as his assistant boss at Tottenham but the Uruguayan insists he has not been approached.
The former Uruguay international, who played for Tottenham between 2001 and 2004 told BBC Sport earlier on Friday: "Everybody is calling me and sending me texts about it but I don't know anything. I haven't spoken to anyone.
"I don't know if something has gone on between the clubs. I don't have a clue."
Leeds said they had not received an approach from Spurs for Poyet - and would not welcome one.
However, the club later revealed Poyet has been asked to stay away from Elland Road for the League One game against Millwall on Saturday.
BBC Sport understands the Spurs board made the decision to sack Jol before the 2-1 defeat to Getafe on Thursday but decided not to inform the Dutchman until after the game.
However, rumours about Jol's imminent departure spread around the ground during the match.
Jol said goodbye to Tottenham's players at the club's training ground on Friday and assistant Chris Hughton and the club's goalkeeping coach Hans Segers have also been dismissed.
BBC So it's official, Ramos has left Sevilla.
I personally think Spurs have made a big mistake, Jol wasn't the problem, the players were. At least they've got a top manager to replace him.